The existence of cancer is based on a fundamental process that occurs in an organism: cell division. A tumor cell breaks the rules of cell division that other cells follow. Cancer can only grow this way if some of the tumor suppressor genes – such as the p53 gene – get mutated in the cancer cells. Then, …
Tag: mutation
Apr 12 2016
Study used CRISPR technology to introduce HIV-resistance mutation into embryos
Researchers from the Guangzhou Medical University in China have reported the use of CRISPR gene editing in human embryos to try to make them resistant to HIV infection. A total of 213 fertilized human eggs were collected from 87 patients of in vitro fertility therapy. The embryos were unsuitable for implantation because they contained an …
Nov 11 2015
Trials in gene editing in humans about to begin in 2017
The biotechnology company Editas hopes to begin clinical trials using the latest gene editing technique on human subjects in 2017, according to the company’s CEO Katrine Bosley. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as plasmids and phages, and provides a form of acquired immunity.
Sep 29 2015
New genes arise from non-coding DNA
For most of the last 40 years, scientists thought that new genes simply arose from copies of existing genes. The old version went on doing its job, and the new copy became free to evolve novel functions. Certain genes, however, have no known relatives, and they bear no resemblance to any other gene. The mystery …