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Adaptations to the CRISPR technology enable production of biofuel precursors in yeast

Yeast, among other microbes, are highly valuable for metabolic engineering because they can produce chemicals and other compounds for biofuels, food, and other industrial products. The yeast Yarrowia lipolytica is an important microbial host for chemical production because it has a high capacity to synthesize, modify, and store intracellular lipids; however, rapid strain development has …

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Genetically-modified monkeys with autism created

Scientists in China say they have created monkeys with a version of autism by genetic engineering, an achievement that could make it easier to test treatments for the condition. Zilong Qiu’s team at the Shanghai Institutes for Biological Sciences has generated more than a dozen monkeys with a genetic error that in human children causes …

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Trials in gene editing in humans about to begin in 2017

The biotechnology company Editas hopes to begin clinical trials using the latest gene editing technique on human subjects in 2017, according to the company’s CEO Katrine Bosley. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as plasmids and phages, and provides a form of acquired immunity.

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Gene editing treat rare liver disease

Using a new system of genetic editing based on bacterial proteins by researchers from MIT cured rare liver disease caused by a single genetic mutation. The findings described in the edition of Nature Biotechnology, provide the first evidence that the technique of editing of a gene known as CRISPR, can reverse disease symptoms. CRISPR, which offers an …

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