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Dagatron Auto Stainer AT-2000GGRAM

Stop hard Manual staining. Exact results from all medical laboratories in the world!

Specimens according to GRAM staining method by automated system control.

This new innovated stainer features advanced functions and performances over manual

staining or automated dip-type stainers, include simplicity and convenience.

It can be provide safety and comfortable environment of test lab.

Accurate and precision Stain

This GRAM Auto Stainer provides fast, easy and stable staining process for staining clinical

Can be used by simple operation and it can be available to obtain accurate and precision stain.


  • No cross-contamination in all of process.
  • Reduction in labor costs.
  • Self cleaning system to clean tray
  • Checking and Warning for lower level of reagents.
  • Minimize personal variation during staining.


AT-2000GGRAM Stainer  
Slide Trey Capacity   1 slide ~10 slides(1 to 20 slides by adding Optional Tray) 
Tray Rotation Speed   Approximately, 6RPM (Stain Mode) / Approximately, 200RPM(DRY Mode) 
Display  4 Line by 20 character alpha-numeric LCD dot-matrix 
Key Button Controls   6 Mode Key(Stain, Prime, Clean, Dry, Reset, Slide up/down)  6 Function selection 
Used Reagent / Consumption(Typical)    Crystal Violet / Gram-lodine / Acetone Alcohol / Safranine 1.2ml~1.8ml 
1 Cycle Stain time(Typical)   10 slides : 13 min. / 20 slides: 18 min.(Option)
Dimensions   480(W) x 445(D) x 265(H)mm. Clearance Height(Lid open): Max. 565mm 
Weight   Approx. 17 kgs
Electrical Requirements   100~240VAC~(Auto selection)@50 to 60 Hz
Power Consumption   Max.50 Watts
Drain Connection   Nipple on rear Panel
Safety   Lid interlock : Lid must be closed, andis locked down during operation 
Standard Accessies   1L Reagent Bottle(1set), 5L Waterbottle(1), Reagent Container(1) Reagent Container cable(1), Powercord(1), Drain hose(1) Ragent connection Tube(1 set), User’smanual(1) Quick installation and user’s guide(1),Spare fuse(1), Carbon filer(5) 
Optional Accessaries   Additional slide for 10 slides


Kronos HT WSL-1565 with Brochure 2019

NEW WSL-1565 Kronos HT Brochure 2019

Download (PDF, 84.55MB)


Kronos HT main unit, Control software (for Windows PC), CO2gas mixer, Humidifying unit, 24 well plate adapter

  • High throughput live cell realtime reporter assay
  • Measuring with temperature and CO2 controlled incubation chamber
  • 24 well plate x 2 or 96 well plate x 2 (option)
  • Data display with real-time
  • Detectors scan each well, so culture plates don’t move.
  • Lower noise by PMT cooling
  • Dual-color luciferase assay by optical filter auto-changing

Detector: Photomultiplier tube (10oC cooling) x 2 units, X-Y actuating
Measurement: Photon counting method
Measurement time: Integral time: 1 – 60 s/well, Measurement term: 1 h – 30 days
Plate format: Clear bottom 24 well plate x 2 (Standard)
Clear bottom 96 well plate x 2 (Option), 35 mm dish x 12 (Option)
48 samples (24 well plate x 2)
192 samples (96 well plate x 2, option)
12 samples (35 mm dish x 12, option)
Incubation temperature control: Room temperature + 5oC to 45oC at room temperature 20 – 28oC
CO2 gas control: Control to 5% by CO2 gas mixer
Setting of water reservoir in incubator and humidified 5% CO2 gas flowing intermittently by
humidifying unit
Maintaining >90%RH
Multi-color assay: Measurement with automatically selected optical filter up to 2 colors
PC requirements OS: Windows 10 / 8.1 / 7, 64 / 32 bit, Memory: 4 GB, HDD: more than 20 GB free space
Interface: USB2.0 x 1 port
Dimensions, Weight:
Main unit: 650 (W) x 520 (D) x 340 (H) mm, 40 kg
CO2 gas mixer: 160 (W) x 300 (D) x 200 (H) mm, 4.8 kg
Humidifying unit: 170 (W) x 140 (D) x 115 (H) mm, 1.6 kg
Main unit: AC 100 – 240 V, 50 / 60 Hz, 400 W (max)
CO2 gas mixer: AC 100 – 240 V, 50 / 60 Hz, 100 W (max)
Humidifying unit: AC 100 – 240 V, 50 / 60 Hz, 24W (max)

Model 3510146: 24 well plate adapter
Model 3510147: 96 well plate adapter
Model 3510148: 35 mm dish adapter

Application data

Circadian rhythm of clock gene expression

Transcriptional activity of clock gene, mPer2
mPer2 promoter – Eluc (PEST) expressed fibroblast stable
cell line in 24 well clear bottom plate
Measurement time: 5s / well, Interval time: 10min

Drug response of transcription factor

Dual-color real-time luciferase assay of TNF-a induced NF-kB transcriptional activity

NF-kB response elemnt – TK promoter – SLG (green color emited luciferase) and TK promoter – SLR (red color emitted luciferase)
expressed fibroblast cell line in 96 well clear bottom plate
Measurement time: 5s x 2 color / well, Interval time: 30min
(A), (B) Transcriptional activity of NF-kB and TK promoter for 48h
(C) Normalized by activity of control (TK)
(D) Ratio to NF-kB activity without TNF-a


Kronos HT WSL-1565

High throughput real-time luciferase assay system

  • High throughput live cell realtime reporter assay
  • Measuring with temperature and CO2 controlled incubation chamber
  • 24 well plate x 2 or 96 well plate x 2 (option)
  • Data display with real-time
  • Detectors scan each well, so culture plates don’t move.
  • Lower noise by PMT cooling
  • Dual-color luciferase assay by optical filter auto-changing


The world’s first baby with three parents was born


A boy is the world’s first baby that has the DNA of three people. The “three parent” technique allows parents with rare genetic mutations to have healthy babies. In this case, the mother carries genes for Leigh syndrome in her mitochondrial genome. She is healthy but had lost her first two children to the disease which affects the brain, muscles and nerves of developing infants.

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Zika vaccine trials begin

Vaccine trial
A vaccine is being given to 160 people in Puerto Rico, and a preliminary study has identified two existing drugs that seem to protect human brain cells from the virus.
The vaccine contains a synthetic DNA fragment similar to one in the virus itself. Hopefully, people who receive it will develop immune protection against Zika.

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Will there be more records to break?


At this month’s Summer Olympics in Rio, the world’s fastest man, Usain Bolt — will try to beat his own world record of 9.58 seconds in the 100-meter dash.
Whereas a great number of training techniques and technologies continue to push the boundaries of athletics, the slowing pace at which sporting records are now broken has researchers speculating that perhaps we’re approaching our collective physiological limit.
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Zika becomes a sexually transmitted infection


The Centers for Disease Control and Prevention (CDC) have confirmed that Zika is already a sexually transmitted disease. Public health experts now know that Zika can be passed in bodily fluids. So far, in the continental United States, 15 cases of Zika are confirmed to have been transmitted by sexual contact. This has been reported in ten other countries, and in the United States, the first known case of sexual transmission was in 2008. Until the giant South American outbreak began, Zika was under-researched, and that was true for sexual transmission of the disease as well.
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Zika calls attention to a common birth-defect virus

E81B0G Conceptual image of human cytomegalovirus. Cytomegalovirus is a genus of the viral family Herpesviridae.

A common and much less exotic virus than Zika is killing hundreds of babies and leaving thousands with severe birth defects, including abnormally small heads and brains, hearing loss and cerebral palsy. It is the cytomegalovirus (CMV).
This virus is a much greater global problem than Zika, but receives much less attention.
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Scientists discover 320 million-year-old plant root stem cells

Radix carbonica

A team of paleontologists led by Oxford University researcher Prof. Liam Dolan has found the oldest known population of plant root stem cells in a fossilized root tip from a Carboniferous coal swamp forest 320 million years old. The discovery was published in the journal Current Biology. In addition to revealing the oldest plant root stem cells identified to date, the research also marks the first time an actively growing fossilized root has been discovered – in effect, an ancient plant frozen in time. Prof. Dolan and his colleagues have named the stem cell fossil Radix carbonica (Latin for ‘coal root’). Continue reading

Evolutionary approach to cancer treatment

Computer artwork depicting a tumour cell dissolving by laser or drug treatment. These tumour cells promote the formation of new blood vessels, a process known as angiogenesis. The tumour cells release angiogenic growth factor proteins that bind to endothelial cells in nearby blood vessels and encourage the growth of new blood vessels from the existing ones. These blood vessels provide the tumour with oxygen and nutrients.

The existence of cancer is based on a fundamental process that occurs in an organism: cell division. A tumor cell breaks the rules of cell division that other cells follow. Cancer can only grow this way if some of the tumor suppressor genes – such as the p53 gene – get mutated in the cancer cells. Then, some corrupt cells do not get fixed. Over time, one of these cells can grow and divide into thousands, then tens of thousands of cancer cells. Eventually there may even be billions of cells in a tumor.
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